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Journal of Negative Results in BioMedicine

Articles

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  1. Content type: Research

    Patients admitted to emergency departments with traumatic brain injury (TBI) are commonly being treated with oral anticoagulants. In contrast to patients without anticoagulant medication, no guidelines, scores...

    Authors: Thomas C. Sauter, Stephan Ziegenhorn, Sufian S. Ahmad, Wolf E. Hautz, Meret E. Ricklin, Alexander Benedikt Leichtle, Georg-Martin Fiedler, Dominik G. Haider and Aristomenis K. Exadaktylos

    Citation: Journal of Negative Results in BioMedicine 2016 15:12

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  2. Content type: Brief report

    SLC4A3 has been shown to cause retinal degeneration in a genetically engineered knockout mouse, and in a naturally occurring form of canine progressive retinal atrophy considered to be the equivalent of retinitis...

    Authors: Louise M. Downs, Andrew R. Webster, Anthony T. Moore, Michel Michaelides, Robin R. Ali, Alison J. Hardcastle and Cathryn S. Mellersh

    Citation: Journal of Negative Results in BioMedicine 2016 15:11

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  3. Content type: Research

    Selective glucocorticoid receptor modulators (SEGRMs) comprise a novel class of drugs promising both reduced side effects and similar pharmacological potency relative to glucocorticoids, which presently serve ...

    Authors: Lukas D. Landegger, Clemens Honeder, Chengjing Zhu, Hanna Schöpper, Elisabeth Engleder, Franz Gabor, Wolfgang Gstoettner and Christoph Arnoldner

    Citation: Journal of Negative Results in BioMedicine 2016 15:10

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  4. Content type: Brief report

    Evidence suggests that vagal nerve activity may play a role in sleep apnea induction. In anesthetized rats, dronabinol, a cannabinoid (CB) receptor agonist, injected into the nodose ganglia attenuates reflex a...

    Authors: Michael W. Calik and David W. Carley

    Citation: Journal of Negative Results in BioMedicine 2016 15:8

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  5. Content type: Research

    Toll-like receptors (TLRs) are involved in a variety of cardiovascular disorders, including septic cardiomyopathy, ischemia/reperfusion, heart failure, and cardiac hypertrophy. Previous research revealed that ...

    Authors: Tippaporn Bualeong, Sied Kebir, Dorothea Hof, Lina Goelz, Mathias Graewe, Stefan Felix Ehrentraut, Pascal Knuefermann, Georg Baumgarten, Rainer Meyer and Heidi Ehrentraut

    Citation: Journal of Negative Results in BioMedicine 2016 15:9

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  6. Content type: Brief report

    Patients with severe aortic stenosis have increased levels of prothrombotic and proinflammatory microparticles (MP), and MPs actively regulate pathological processes that lead to atherothrombotic cardiovascula...

    Authors: Julio F. Marchini, Ayumi Aurea Miyakawa, Flavio Tarasoutchi, José Eduardo Krieger, Pedro Lemos and Kevin Croce

    Citation: Journal of Negative Results in BioMedicine 2016 15:7

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  7. Content type: Research

    Recently, topical dexamethasone-induced ocular hypertension and a consequent loss of retinal ganglion cells (RGCs) have been described in mice. This has been proposed as a model of steroid-induced glaucoma. In...

    Authors: Kota Sato, Koji M. Nishiguchi, Kazuichi Maruyama, Satoru Moritoh, Kosuke Fujita, Yoshikazu Ikuta, Hitoshi Kasai and Toru Nakazawa

    Citation: Journal of Negative Results in BioMedicine 2016 15:5

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  8. Content type: Research

    The diagnosis of community-acquired pneumonia (CAP) caused by Legionella pneumophila, Mycoplasma pneumoniae, and Chlamydophila pneumoniae is traditionally based on cultures and serology, which have special requir...

    Authors: Mariana Herrera, Yudy Alexandra Aguilar, Zulma Vanessa Rueda, Carlos Muskus and Lázaro Agustín Vélez

    Citation: Journal of Negative Results in BioMedicine 2016 15:3

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  9. Content type: Research

    Patients with diuretic therapy are at risk for drug-induced adverse reactions. It is unknown if presence of diuretic therapy at hospital emergency room admission is associated with mortality.

    Authors: Dominik G. Haider, Gregor Lindner, Michael Wolzt, Alexander Benedikt Leichtle, Georg-Martin Fiedler, Thomas C. Sauter, Valentin Fuhrmann and Aristomenis K. Exadaktylos

    Citation: Journal of Negative Results in BioMedicine 2016 15:1

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  10. Content type: Commentary

    Mobile phone use has been discussed over the last few decades with increased risk for intracranial tumors. The majority of studies have been conducted on gliomas and meningiomas. Although some case-control stu...

    Authors: George A. Alexiou and Chrissa Sioka

    Citation: Journal of Negative Results in BioMedicine 2015 14:23

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  11. Content type: Brief report

    Ensuring genetic stability in pluripotent stem cell (PSC) cultures is essential for the development of successful cell therapies. Although most instances lead to failed experiments and go unreported in the lit...

    Authors: Suehelay Acevedo-Acevedo and Wendy C. Crone

    Citation: Journal of Negative Results in BioMedicine 2015 14:22

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  12. Content type: Brief report

    Omega–3 fatty acids prevent cardiovascular disease (CVD) events in patients with myocardial infarction or heart failure. Benefits in patients without overt CVD have not been demonstrated, though most studies d...

    Authors: Mori J. Krantz, Edward P. Havranek, Rocio I. Pereira, Brenda Beaty, Philip S. Mehler and Carlin S. Long

    Citation: Journal of Negative Results in BioMedicine 2015 14:21

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  13. Content type: Research

    Ethanol exposure during the rodent equivalent to the 3rd trimester of human pregnancy (i.e., first 1–2 weeks of neonatal life) has been shown to produce structural and functional alterations in the CA3 hippocampa...

    Authors: Brian Charles Baculis and Carlos Fernando Valenzuela

    Citation: Journal of Negative Results in BioMedicine 2015 14:19

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  14. Content type: Brief report

    Polymorphisms in the TNF-A gene have been associated with chronic obstructive pulmonary disease (COPD) in some case-control studies. Previous work has shown that COPD/chronic bronchitis subjects with alpha-1 a...

    Authors: Jennie M. Gane, Robert A. Stockley and Elizabeth Sapey

    Citation: Journal of Negative Results in BioMedicine 2015 14:20

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  15. Content type: Research

    This study aims to better define prognostic factors for patients with metastatic urothelial carcinoma (mUC), and to identify patients who will benefit from first-line cisplatin-based chemotherapy. We test the ...

    Authors: Guilhem Roubaud, Véronique Brouste, Phillipe Beuzeboc, Aude Fléchon, Diego Tosi, Sandrine Lavau-Denes, Christine Chevreau, Stéphane Culine, Stéphane Oudard, Amandine Quivy, Philippe Pourquier and Nadine Houédé

    Citation: Journal of Negative Results in BioMedicine 2015 14:18

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  16. Content type: Brief report

    Willis-Ekbom disease (WED), also called restless legs syndrome (RLS), is a neurologic sensorimotor disease that may be associated with cardiovascular disease. Given high morbidity and mortality rates of cardiovas...

    Authors: Brynn K. Dredla, Oscar H. Del Brutto, Augustine S. Lee and Pablo R. Castillo

    Citation: Journal of Negative Results in BioMedicine 2015 14:17

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  17. Content type: Brief report

    In this study, we aimed to identify microRNA from urine of multiple myeloma patients that could serve as a biomarker for the disease.

    Authors: Lenka Sedlaříková, Lenka Bešše, Soňa Novosadová, Veronika Kubaczková, Lenka Radová, Michal Staník, Marta Krejčí, Roman Hájek and Sabina Ševčíková

    Citation: Journal of Negative Results in BioMedicine 2015 14:16

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  18. Content type: Research

    Azithromycin prophylaxis has been shown to reduce COPD exacerbations but there is poor evidence for other antibiotics. We compared exacerbation rates in COPD patients with a history of frequent exacerbations (...

    Authors: Eskandarain Shafuddin, Graham D. Mills, Mark D. Holmes, Phillippa J. Poole, Peter R. Mullins and Peter N. Black

    Citation: Journal of Negative Results in BioMedicine 2015 14:15

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  19. Content type: Research

    The genome, the environment, and their interactions simultaneously regulate complex traits such as body composition and voluntary exercise levels. One such environmental influence is the maternal milieu (i.e.,...

    Authors: Scott A. Kelly, Kunjie Hua, Jennifer N. Wallace, Sarah E. Wells, Derrick L. Nehrenberg and Daniel Pomp

    Citation: Journal of Negative Results in BioMedicine 2015 14:13

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  20. Content type: Research

    Brain morphometric abnormalities in schizophrenia have been extensively reported in the literature. Whole-brain volumetric reductions are almost universally reported by most studies irrespective of the charact...

    Authors: John P. John, Ammu Lukose, Bhavani Shankara Bagepally, Harsha N. Halahalli, Nagaraj S. Moily, Anupa A. Vijayakumari and Sanjeev Jain

    Citation: Journal of Negative Results in BioMedicine 2015 14:11

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