Fig. 4
From: Does the placebo effect modulate drug bioavailability? Randomized cross-over studies of three drugs
Average bioequivalence evaluation of covert-overt cephalexin, ibuprofen, and paracetamol. Data represent point estimate (antilog of mean covert-overt difference of log-transformed values) and parametric 90% confidence interval. The shaded area indicates the area of bioequivalence (80.00% to 125.00%). a, bioequivalence evaluation of area-under-the-concentration-time curve to last quantifiable concentration (AUCT). b, bioequivalence evaluation of area-under-the-concentration-time curve extrapolated to infinity (AUCI). c, bioequivalence evaluation of maximum concentration (Cmax). d, bioequivalence evaluation of area-under-the-concentration-time curve extrapolated to overt Tmax (AUCOverttmax). e, bioequivalence evaluation of Cmax/AUCI