Diabetic Nephropathy | Normoalbuminuria | P-value | |
---|---|---|---|
Patient characteristics | |||
N (% male) | 448 (60.9) | 419 (54.4) | p = 0.02 |
Age (years) | 42.2 ± 10.5 | 45.3 ± 11.5 | p < 0.001 |
Duration of DM (years) | 28.2 ± 8.7 | 27.8 ± 10.1 | p = 0.025 |
BMI (kg/m2) | 24.2 ± 3.3 | 24.1 ± 2.9 | p = 0.7 |
Retinopathy (nil/simplex/proliferative) | 7/135/306 | 151/159/109 | p < 0.001 |
Antihypertensiva (no/yes) | 95/308 | 351/68 | p < 0.001 |
Smokers (%) | 46 | 39 | p = 0.05 |
Glycemic control | |||
Blood glucose (mmol/l) | 11.0 ± 5.4 | 9.4 ± 4.7 | p < 0.001 |
HbA1c (%) | 9.4 ± 1.5 | 8.4 ± 1.1 | p < 0.001 |
Parameters of Nephropathy | |||
UAE (mg/24 h) | 593.1 (250.0-1519.5) | 7.0 (4.0-12.0) | p < 0.001 |
Plasma creatinine (μmol/l) | 102 (82.0-136.3) | 79 (53-81) | p < 0.001 |
GFR (ml/min/1.73 m2) | 66.1 ± 27.7 | 87.4 ± 14.9 | p < 0.001 |
ESRD (%male) | 24 (70.8) | 0 | p < 0.001 |
Systolic Blood Pressure (mm Hg) | 144.3 ± 21.8 | 133.8 ± 18.6 | p < 0.001 |
Diastolic Blood Pressure (mm Hg) | 82.5 ± 12.2 | 76.1 ± 9.6 | p < 0.001 |