Table 3 Effect of rs547984 genotypes on demographic and clinical characteristics within PAOG group
Characteristics | Genotypes | p valuea | ||
|---|---|---|---|---|
C/C (n = 20) No. (%) | C/A (n = 52) No. (%) | A/A (n = 18) No. (%) | ||
DEMOGRAPHIC | ||||
Age in years, Mean (SD) | 58.6 (13.8) | 61.5 (12.1) | 60.5 (11.6) | 0.674b |
Male | 13 (65.0) | 33 (63.4) | 9 (50.0) | 0.553 |
Female | 7 (35.0) | 19 (57.5) | 9 (50.0) | - |
MEDICAL HISTORY | ||||
Family history of glaucoma | 4 (20.0) | 9 (17.3) | 1 (5.5) | 0.408 |
Smoking | 10 (50.0) | 18 (34.6) | 6 (33.3) | 0.440 |
Diabetes mellitus | 13 (65.0) | 27 (51.9) | 9 (50.0) | 0.556 |
Hypertension | 9 (45.0) | 28 (53.8) | 10 (55.5) | 0.758 |
Coronary artery disease | 2 (10.0) | 4 (76.9) | 0 (0.0) | 0.421 |
Hypercholesterolemia | 5 (25.0) | 9 (17.3) | 0 (0.0) | 0.091 |
GLAUCOMA INDICES | ||||
Intraocular pressure in mmHg, mean (SD) | 33.9 (6.1) | 35.2 (8.3) | 31.3 (5.7) | 0.206c |
Cup/disc ratio | 0.69 (0.19) | 0.74 (0.16) | 0.65 (0.23) | 0.285c |
No. of anti-glaucoma medications | 2.8 (0.6) | 2.8 (0.8) | 2.4 (0.6) | 0.065c |