Table 3 Effect of genotypes on demographic and clinical characteristics within PAOG cases
From: Lack of association between polymorphism rs540782 and primary open angle glaucoma in Saudi patients
Characteristics | Genotypes | p valuea | ||
|---|---|---|---|---|
G/G (n = 22) No. (%) | G/C (n = 54) No. (%) | C/C (n = 16) No. (%) | ||
Demographic | ||||
Age in years, Mean (SD) | 59.0 (13.5) | 61.5 (12.0) | 60.2 (12.0) | 0.713* |
Male | 14 (25.0) | 34 (60.7) | 8 (14.2) | 0.617 |
Female | 8 (22.2) | 20 (55.5) | 8 (22.2) | - |
Medical history | ||||
Family history of glaucoma | 4 (28.5) | 9 (64.2) | 1 (7.1) | 0.613 |
Diabetes mellitus | 13 (26.5) | 28 (57.1) | 8 (16.3) | 0.813 |
Smoking | 11 (32.3) | 17 (50.0) | 6 (17.6) | 0.316 |
Hypertension | 10 (20.8) | 30 (62.5) | 8 (16.6) | 0.713 |
Coronary artery disease | 2 (28.5) | 4 (57.1) | 1 (14.2) | 0.944 |
Hypercholesterolemia | 5 (33.3) | 8 (53.3) | 2 (13.3) | 0.630 |
Glaucoma indices | ||||
Intraocular pressure in mmHg, Mean (SD) | 33.2 (6.2) | 34.7 (8.6) | 31.9 (5.7) | 0.474** |
Cup/disc ratio | 0.68 (0.19) | 0.74 (0.15) | 0.64 (0.24) | 0.243** |
No. of anti-glaucoma medications | 2.8 (0.6) | 2.8 (0.8) | 2.5 (0.6) | 0.122** |