Table 2 Association results of SNP rs540782 with genotype and allele frequency distribution in POAG and controls
From: Lack of association between polymorphism rs540782 and primary open angle glaucoma in Saudi patients
SNP (Gene) | rs540782 (ZP4) | ||||
|---|---|---|---|---|---|
Allelic analysis | Controls (n = 95) No. (%) | POAG (n = 92) No. (%) | Odds ratio | 95% confidence interval | p valuea |
G | 96 (50.5) | 98 (53.2) | 1 | Reference | - |
C* | 94 (49.4) | 86 (46.7) | 1.11 | 0.74–1.67 | 0.60 |
HWE P | 0.76 | 0.09 | - | - | - |
Genotype and Model analysis | |||||
G/G | 25 (26.3) | 22 (23.9) | 1 | Reference | - |
C/G | 46 (48.4) | 54 (58.7) | 0.75 | 0.37–1.50 | 0.48 |
C/C | 24 (25.2) | 16 (17.4) | 1.32 | 0.56–3.09 | 0.66 |
Additive (Trend) | - | - | - | - | 0.30§ |
Dominant | - | - | 0.88 | 0.45–1.70 | 0.70 |
Recessive | - | - | 1.16 | 0.54–2.0 | 0.69 |