Low density lipoprotein receptor-related protein 5 gene polymorphisms and osteoporosis in Thai menopausal women

Table 4 Association between LRP5 genotypes and parameters of studied population

Characteristic	rs3736228		p-value	rs41494349		p-value	rs2306862		p-value
Characteristic	CC	CT	p-value	AA	AG+GG	p-value	CC	CT+TT	p-value
Age (years)	58 (45–73)	55 (45–75)	0.002	58 (45–75)	57 (45–72)	0.989	58 (45–73)	56 (45–75)	0.224
N	210	67		245	30		193	68	0.224
BMI (kg/m²)	22.77 (15.46–39.54)	22.88 (18.75–33.91)	0.804	22.77 (15.46–39.54)	23.14 (19.34–30.47)	0.878	22.55 (15.46–39.54)	23.06 (18.44–33.91)	0.350
N	210	67		245	30		193	68	0.350
Lumbar spine BMD (g/cm²)	1.018 (0.700–1.564)	0.983 (0.778–1.555)	0.584	1.013 (0.700–1.564)	1.003 (0.778–1.353)	0.388	1.013 (0.700–1.564)	0.993 (0.778–1.555)	0.787
N	160	45		183	22		147	46	0.787
Femoral neck BMD (g/cm²)	0.787 (0.434–1.204)	0.789 (0.612–1.224)	0.728	0.785 (0.434–1.204)	0.831 (0.562–1.224)	0.154	0.785 (0.434–1.141)	0.788 (0.548–1.224)	0.905
N	178	55		210	23		165	56	0.905
Total radial BMD (g/cm²)	0.469 (0.265–0.961)	0.500 (0.262–0.623)	0.011	0.475 (0.262–0.961)	0.475 (0.353–0.584)	0.702	0.471 (0.265–0.961)	0.485 (0.262–0.623)	0.191
N	210	67		245	30		193	68	0.191
Radial 33 BMD (g/cm²)	0.614 (0.315–0.785)	0.657 (0.350–0.818)	0.001	0.623 (0.315–0.818)	0.634 (0.447–0.722)	0.769	0.613 (0.315–0.785)	0.649 (0.350–0.818)	0.015
N	210	67		245	30		193	68	0.015
Total hip BMD (g/cm²)	0.870 (0.229–1.281)	0.875 (0.636–1.322)	0.565	0.870 (0.229–1.322)	0.909 (0.600–1.252)	0.625	0.869 (0.229–1.281)	0.876 (0.636–1.322)	0.636
N	178	55		210	23		165	56	0.636

ISSN: 1477-5751