Fig. 1
From: Investigation of SLA4A3 as a candidate gene for human retinal disease
Genomic structure of the human SLC4A3 gene and AE3 protein isoforms. a The three isoforms of SLC4A3 are created by alternative splicing of exons 1–6 and C1, and by alternative splicing of exon 6 (red). b AE3fl1 and AE3fl2 proteins are created from alternative splicing of exon 6 and differ only with regards to the presence and absence respectively of 27 amino acids. AE3c is created by alternative splicing of exon C1 and the first 72 amino acids are completely different than the full-length isoforms (grey). All three isoforms are identical over the 962 amino acids at the C-terminal end