Table 1 Total cholesterol and ALT in blood samples increased after topical dexamethasone treatment. Blood samples were analyzed after 4 weeks of treatment. All data are expressed as the mean ± standard deviation (N = 6)
From: Topical ocular dexamethasone decreases intraocular pressure and body weight in rats
Terms | Unit | Vehicle | DEX | p value |
|---|---|---|---|---|
Albumin | (g/dL) | 4.15 ± 0.12 | 4.05 ± 0.36 | 0.5359 |
ALP | (IU/L) | 525.5 ± 74.9 | 656.8 ± 169 | 0.117 |
ALT (GPT) | (IU/L) | 57.0 ± 23.1 | 190.7 ± 169 | 0.0197 |
AST (GOT) | (IU/L) | 93.5 ± 23.4 | 164.7 ± 89.8 | 0.0897 |
Calcium | (mg/dL) | 10.3 ± 0.32 | 10.1 ± 0.35 | 0.29 |
Chloride | (mEQ/L) | 102.0 ± 1.91 | 101.0 ± 1.67 | 0.2487 |
Cholineesterase | (IU/L) | 6.83 ± 2.04 | 5.50 ± 0.55 | 0.1533 |
Creatinine | (mg/dL) | 0.26 ± 0.03 | 0.20 ± 0.04 | 0.0132 |
Free fatty acid | (μEQ/L) | 176.7 ± 80.0 | 382.7 ± 245.6 | 0.0793 |
Glucose | (mg/dL) | 169.7 ± 13.2 | 166.2 ± 57.9 | 0.888 |
HbA1c (NGSP) | (%) | 4.87 ± 0.37 | 5.55 ± 0.92 | 0.12234 |
Inorganic phosphorus | (mg/dL) | 7.57 ± 0.56 | 8.30 ± 1.67 | 0.331 |
Potassium | (mEQ/L) | 4.78 ± 0.50 | 4.82 ± 1.08 | 0.9466 |
Sodium | (mEQ/L) | 143.8 ± 0.98 | 145.2 ± 1.60 | 0.1129 |
Total cholesterol | (mg/dL) | 70.0 ± 16.8 | 230.5 ± 37.6 | <0.0001 |
Total protein | (g/dL) | 6.23 ± 0.32 | 6.35 ± 0.37 | 0.5739 |
Triglyceride | (mg/dL) | 165.2 ± 63.3 | 208.2 ± 47.2 | 0.2119 |
Urea nitrogen | (mg/dL) | 18.62 ± 1.56 | 19.28 ± 2.42 | 0.583 |
γ – GTP | (IU/L) | <3 | <3 |