Skip to main content
Fig. 2 | Journal of Negative Results in BioMedicine

Fig. 2

From: The rs361525 polymorphism does not increase production of tumor necrosis factor alpha by monocytes from alpha-1 antitrypsin deficient subjects with chronic obstructive pulmonary disease - a pilot study

Fig. 2

TNF-α production over time by monocytes from patients with and without the rs361525 TNF-α polymorphism. a ∆CT values for TNF-α mRNA expression (normalised to GAPDH) in un-stimulated monocytes cultured over 24 hours. b Concentration of sTNF-α in the supernatant of un-stimulated monocytes cultured for 6 and 24 hours. c ∆CT values for TNF-α mRNA expression in LPS-stimulated monocytes cultured over 24 hours. d Concentration of sTNF-α in the supernatant of LPS-stimulated monocytes cultured for 6 and 24 hours. Results are displayed as median (with IQR). There was no significant increase in TNF-α mRNA expression or protein concentration in the AG monocyte group

Back to article page