Fig. 5
From: Sutherlandia frutescens may exacerbate HIV-associated neuroinflammation
Schematic representation of inflammatory signalling pathways associated with HIV-1 infection. Novel mechanism of action elucidated by current data is indicated with a green star. Abbreviations: Mitogen activated protein kinase (MAPK); Extracellular signal-regulated kinase 1/2(ERK1/2); c-Jun N-terminal Kinase (JNK); Early Growth Response protein-1 (Egr-1); NLRP3 – NOD-like receptor family, pyrine domain containing 3