Figure 2

Macroscopic aspects of periodontium of rats submitted to EPD and treated with venlafaxine. A sham operated (SO) with no resorption of the alveolar bone when compared to the untreated group (EPD), where severe bone resorption with root exposure is observed B. Figure 2C and 2D shows the periodontium subjected to EPD and treated with venlafaxine (10 or 50 mg/kg, administered orally 1 hour before ligature placement and daily for 10 days) where severe bone loss is observed. Original magnification × 1.5.