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Table 1 Characteristics of demographic, biochemistry, and oxidative stress marker variables in dialysis and healthy subjects

From: Lack of association between mutations of gene-encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan

 

Dialysis patients

Control group

 
 

N = 184

N = 213

P -value

Age

48.3 ± 14.2

49.2 ± 13.6

0.495

Gender (male)

71

83

0.938

BMI

22.1 ± 3.4

23.8 ± 3.7

0.000

Systolic BP (mmHg)

134 ± 25

130 ± 20

0.058

Diastolic BP (mmHg)

77 ± 14

82 ± 12

0.000

TBARS (μM/L)

1.126 ± 0.628

0.771 ± 0.478

0.000

Free thiol (μM/L)

1.515 ± 0.457

2.110 ± 0.423

0.000

mtDNA copy number

1664 ± 2551

412 ± 270

0.000

Hemoglobin (g/dl)

10.2 ± 1.7

14.0 ± 1.5

0.000

Hematocrit (%)

31.1 ± 5.4

42.2 ± 4.0

0.000

BUN (mg/dl)

68.6 ± 18.1

13.9 ± 4.2

0.000

Creatinine (mg/dl)

12.5 ± 2.7

1.0 ± 0.2

0.000

Sodium (mEq/L)

137 ± 4

141 ± 2

0.000

Potassium (mEq/L)

4.4 ± 0.8

4.2 ± 0.3

0.001

Calcium (mg/dl)

9.3 ± 1.0

9.1 ± 0.4

0.006

Phosphate (mg/dl)

5.1 ± 1.5

3.5 ± 0.5

0.000

Albumin (g/dl)

3.8 ± 0.4

4.3 ± 0.3

0.000

Blood sugar (mg/dl)

113 ± 47

101 ± 33

0.004

Total cholesterol (mg/dl)

190 ± 34

200 ± 37

0.006

Triglyceride (mg/dl)

162 ± 127

132 ± 133

0.018

  1. Data presented as means ± standard deviation (SD) or (%). The Mann-Whitney test was used for ANOVA to compare groups (p < 0.05). TBARS, thiobarbituric acid reactive substances; mtDNA, mitochondrial DNA.
  2. Comparison demographic, biochemistry, oxidative stress markers
  3. variables in dialysis and healthy subjects. Lower levels of albumin, cholesterol, and sodium in the dialysis patients as compared to the control subjects. The levels of oxidative stress variables markers and levels of blood TBARS and mtDNA copy numbers were higher in the dialysis patients than in the control subjects, while the blood free thiol levels were lower in the dialysis patients than the control subjects