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Table 4 Impact of the PLIN rs894160 SNP on clinical variables in men and women separately

From: Study of the impact of perilipin polymorphisms in a French population

 

Men

Women

 

GG

281

GA

235

AA

54

GG

272

GA

231

AA

39

Weight, kg

80.2 ± 14.1

79.2 ± 12.8

81.1 ± 13.2

67.5 ± 14.1

69.9 ± 14.6

67.9 ± 16.8

BMI, kg/m2

26.9 ± 4.3

26.3 ± 4.0

26.3 ± 3.7

26.2 ± 5.3

27.0 ± 5.4

26.7 ± 7.1

Waist, cm

96.5 ± 11.4

95.5 ± 10.2

96.3 ± 10.3

84.7 ± 13.4

87.0 ± 14.1

84.3 ± 16.9

Hip circ., cm

101.7 ± 7.5

101.4 ± 7.3

101.4 ± 7.1

102.9 ± 11.1

104.6 ± 11.8

103.7 ± 15.5

WHR

0.95 ± 0.07

0.94 ± 0.07

0.95 ± 0.07

0.82 ± 0.08

0.83 ± 0.08

0.81 ± 0.07

Leptin, ng/mL

9.60 ± 7.90

9.18 ± 7.55

8.24 ± 6.19

23.12 ± 13.72

25.26 ± 14.52

23.79 ± 13.28

Cholesterol, mmol/L

5.93 ± 1.10

5.83 ± 1.00

5.86 ± 0.90

5.90 ± 1.18

6.01 ± 1.05

5.93 ± 1.11

HDL-chol., mmol/L

1.33 ± 0.41

1.37 ± 0.41

1.24 ± 0.37

1.65 ± 0.51

1.68 ± 0.47

1.69 ± 0.43

LDL-chol., mmol/L

3.90 ± 1.05

3.79 ± 0.96

3.99 ± 0.85

3.69 ± 1.10

3.80 ± 0.99

3.68 ± 1.05

Triglycerides, mmol/L

1.71 ± 1.42

1.57 ± 1.31

1.68 ± 1.66

1.21 ± 0.87

1.19 ± 0.97

1.16 ± 0.77

Glucose, mmol/L

5.56 ± 0.90

5.49 ± 0.85

5.27 ± 0.64*

5.40 ± 1.41

5.42 ± 1.71

5.64 ± 1.55

Insulin, μU/mL

12.52 ± 9.48

11.93 ± 8.16

12.83 ± 13.62

11.47 ± 5.86

11.83 ± 5.87

12.43 ± 7.32

  1. *crude p < 0.03 or p < 0.04 when adjusted for age, BMI, smoking and alcohol consumptions with a recessive model (adjusted means 5.51 ± 0.05 for GG vs 5.52 ± 0.05 for GA vs 5.28 ± 0.11 for AA subjects). These variables were log-transformed to obtain normal distributions. Circ. : circumference. WHR : waist-to-hip ratio. Chol. : cholesterol. Among the 1120 individuals genotyped, data on several variables were missing for few subjects.