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Table 1 Clinical characteristics of study subjects by ND2-237 Leu/Met genotype

From: Unexpected combined effects of NADH dehydrogenase subunit-2 237 Leu/Met polymorphism and green tea consumption on renal function in male Japanese health check-up examinees: a cross-sectional study

 

ND2-237Leu

ND2-237Met

P value

 

N = 239

N = 155

 

Age (y)

54.3 ± 7.8

53.2 ± 7.8

0.171

Body mass index (kg/m2)

23.3 ± 2.8

23.5 ± 2.6

0.461

Systolic blood pressure (mmHg)

125.8 ± 15.9

125.7 ± 14.1

0.940

Diastolic blood pressure (mmHg)

74.0 ± 10.7

73.8 ± 9.1

0.823

Serum total cholesterol (mg/dl)

203.5 ± 34.3

202.1 ± 31.8

0.672

Serum HDL cholesterol (mg/dl)

54.6 ± 13.6

56.3 ± 16.2

0.269

Serum triglyceride (mg/dl)

136.7 ± 91.1

139.5 ± 90.8

0.766

Fasting plasma glucose (mg/dl)

97.2 ± 9.4

97.6 ± 9.7

0.672

Serum uric acid (mg/dl)

5.98 ± 1.21

5.93 ± 1.21

0.673

Blood urea nitrogen (mg/dl)

15.8 ± 3.7

15.2 ± 3.4

0.143

Serum creatinine (mg/dl)

0.817 ± 0.117

0.797 ± 0.111

0.090

eGFR (ml/min/1.73 m2)

79.1 ± 13.1

81.5 ± 12.4

0.066

Renal function (eGFR ≥ 90/ 90 > eGFR ≥ 60/ eGFR < 60) (%)

17.6/77.8/4.6

25.2/72.2/2.6

0.133

Antihypertensive medications (%)

18.8

12.9

0.122

Green tea consumption (≤1 cups per day/2-3 cups per day/4-5 cups per day/≥6 cups per day) (%)

26.8/30.1/21.8/21.3

27.7/33.6/20.0/18.7

0.840

Alcohol consumption (daily/occasionally/non-) (%)

46.4/35.2/18.4

47.7/38.7/13.6

0.426

Smoking status (non- or ex-/ 1–20 cigarettes per day/ >20 cigarettes per day) (%)

59.4/29.7/10.9

59.4/25.8/14.8

0.429

Coffee consumption (≤1 cup per day/2-3 cups per day/≥4 cups per day) (%)

61.1/29.7/9.2

55.5/32.9/11.6

0.510

  1. HDL: high-density lipoprotein. eGFR: estimated glomerular filtration rate. Age, body mass index, systolic blood pressure, diastolic blood pressure, serum total cholesterol levels, serum HDL cholesterol levels, serum triglyceride levels, fasting plasma glucose levels, serum uric acid levels, blood urea nitrogen levels, serum creatinine levels and eGFR are given as means ± S.D. For renal function, antihypertensive medications, green tea consumption, alcohol consumption, smoking status and coffee consumption, P values were calculated by chi-squared test. All P values depict significance of differences between ND2-237Leu and ND2-237Met.