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Table 1 Clinical characteristics of study subjects by ND2-237 Leu/Met genotype

From: Unexpected combined effects of NADH dehydrogenase subunit-2 237 Leu/Met polymorphism and green tea consumption on renal function in male Japanese health check-up examinees: a cross-sectional study

  ND2-237Leu ND2-237Met P value
  N = 239 N = 155  
Age (y) 54.3 ± 7.8 53.2 ± 7.8 0.171
Body mass index (kg/m2) 23.3 ± 2.8 23.5 ± 2.6 0.461
Systolic blood pressure (mmHg) 125.8 ± 15.9 125.7 ± 14.1 0.940
Diastolic blood pressure (mmHg) 74.0 ± 10.7 73.8 ± 9.1 0.823
Serum total cholesterol (mg/dl) 203.5 ± 34.3 202.1 ± 31.8 0.672
Serum HDL cholesterol (mg/dl) 54.6 ± 13.6 56.3 ± 16.2 0.269
Serum triglyceride (mg/dl) 136.7 ± 91.1 139.5 ± 90.8 0.766
Fasting plasma glucose (mg/dl) 97.2 ± 9.4 97.6 ± 9.7 0.672
Serum uric acid (mg/dl) 5.98 ± 1.21 5.93 ± 1.21 0.673
Blood urea nitrogen (mg/dl) 15.8 ± 3.7 15.2 ± 3.4 0.143
Serum creatinine (mg/dl) 0.817 ± 0.117 0.797 ± 0.111 0.090
eGFR (ml/min/1.73 m2) 79.1 ± 13.1 81.5 ± 12.4 0.066
Renal function (eGFR ≥ 90/ 90 > eGFR ≥ 60/ eGFR < 60) (%) 17.6/77.8/4.6 25.2/72.2/2.6 0.133
Antihypertensive medications (%) 18.8 12.9 0.122
Green tea consumption (≤1 cups per day/2-3 cups per day/4-5 cups per day/≥6 cups per day) (%) 26.8/30.1/21.8/21.3 27.7/33.6/20.0/18.7 0.840
Alcohol consumption (daily/occasionally/non-) (%) 46.4/35.2/18.4 47.7/38.7/13.6 0.426
Smoking status (non- or ex-/ 1–20 cigarettes per day/ >20 cigarettes per day) (%) 59.4/29.7/10.9 59.4/25.8/14.8 0.429
Coffee consumption (≤1 cup per day/2-3 cups per day/≥4 cups per day) (%) 61.1/29.7/9.2 55.5/32.9/11.6 0.510
  1. HDL: high-density lipoprotein. eGFR: estimated glomerular filtration rate. Age, body mass index, systolic blood pressure, diastolic blood pressure, serum total cholesterol levels, serum HDL cholesterol levels, serum triglyceride levels, fasting plasma glucose levels, serum uric acid levels, blood urea nitrogen levels, serum creatinine levels and eGFR are given as means ± S.D. For renal function, antihypertensive medications, green tea consumption, alcohol consumption, smoking status and coffee consumption, P values were calculated by chi-squared test. All P values depict significance of differences between ND2-237Leu and ND2-237Met.