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Table 3 NOD2 Haplotype Association Analysis

From: Clinical predictors of inflammatory bowel disease in a genetically well-defined Caucasian population

 

SNPs

 

Haplotype Frequencies

 
  

Haplotype

Control

CD

UC

CD and UC combined

p- value (CD vs. UC)

 

rs574329 - rs2066844

C-C

1.34

6.46

1.97

4.75

< 0.0001

 

rs574329 - rs2066845

C-G

1.47

5.3

1.97

4.02

0.004

NOD-2 gene

 

C-C

0

1.18

0

0.74

0.027

 

rs2066844- rs2066845

C-C

1.13

3.54

1.09

2.64

0.009

 

rs574329 - rs2066844- rs2066845

C-C-G

1.35

5.27

1.97

4.01

0.008

  

C-C-C

0

1.19

0

0.75

0.018