Table 4 NGFR haplotypes and the risk of Alzheimer's disease
From: Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease
Haplotype | Frequency among controls (%) | Co-dominant model | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | 0 copies | 1 copy | 2 copies | |||||
| Â | Â | Case/control | OR | Case/control | OR (95% CI) | p | Case/control | OR (95% CI) | p |
Hap1: GCGCG | 27.8 | 148/203 | 1.00 | 105/156 | 0.82 (0.54-1.25) | 0.36 | 11/30 | 0.39 (0.17-0.91) | 0.03 |
Hap2: GCTTG | 21.9 | 159/234 | 1.00 | 90/140 | 0.94 (0.61-1.47) | 0.79 | 15/15 | 1.01 (0.42-2.42) | 0.99 |
Hap3: GCTTA | 11.5 | 205/305 | 1.00 | 56/78 | 1.09 (0.65-1.84) | 0.74 | 3/6 | 1.38 (0.27-6.97) | 0.70 |
Hap4: GCTCA | 11.3 | 197/304 | 1.00 | 65/81 | 1.37 (0.83-2.27) | 0.22 | 2/4 | 0.94 (0.11-7.94) | 0.95 |
Hap5: GTTCG | 10.3 | 213/312 | 1.00 | 47/74 | 1.37 (0.81-2.33) | 0.23 | 4/3 | 3.59 (0.66-19.42) | 0.14 |
Hap6: GCTCG | 8.9 | 217/323 | 1.00 | 46/63 | 0.97 (0.54-1.73) | 0.92 | 1/3 | 0.18 (0.01-5.26) | 0.32 |
Hap7: TCTCG | 5.6 | 230/347 | 1.00 | 34/40 | 1.15 (0.63-2.12) | 0.65 | 0/2 | NA | Â |
Global test P = 0.27 | |||||||||