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Table 1 Clinical and demographic data of the study population used for ex vivo gene expression analysis (age, sex, diagnosis, Thompson grade [29], vertebral level)

From: Human MMP28 expression is unresponsive to inflammatory stimuli and does not correlate to the grade of intervertebral disc degeneration

Sample

Sex

Age

Diagnosis

Grade

Level

Region

1

M

31

DDD

II

L5/S1

NP

2a

F

39

Trauma

II

C4/5

AF

2b

F

39

Trauma

II

C4/5

NP

3a

F

57

Trauma

II

Th10/11

AF

3b

F

57

Trauma

II

Th10/11

NP

4a

F

70

Trauma

II

Th12/L1

AF

4b

F

70

Trauma

II

Th12/L1

NP

5a

M

29

Trauma

III

L1/2

AF

5b

M

29

Trauma

III

L1/2

NP

6a

F

34

DDD

III

L4/5

AF

6b

F

34

DDD

III

L4/5

NP

7a

M

41

DDD

III

C4/5

AF

7b

M

41

DDD

III

C4/5

NP

8

M

46

DDD

III

L5/6

NP

9a

M

25

DDD

IV

L5/S1

AF

9b

M

25

DDD

IV

L5/S1

NP

10

M

44

DDD

IV

L5/S1

AF+NP

11

M

50

DDD

IV

L5/S1

AF+NP

12

M

55

Spondylodesis

IV

C3/4

AF+NP

13a

F

58

Spondylodesis

IV

C5/6

AF

13b

F

58

Spondylodesis

IV

C5/6

NP

14

M

37

DDD

V

L5/S1

AF+NP

15a

F

41

DDD

V

L3/4

AF

15b

F

41

DDD

V

L3/4

NP

16a

M

67

DDD

V

L5/S1

AF

16b

M

67

DDD

V

L5/S1

NP

17a

M

72

DDD

V

L4/5

AF

17b

M

72

DDD

V

L4/5

NP

  1. M = male, F = female, NP = nucleus pulposus, AF = annulus fibrosus. DDD = degenerative disc disease, C = cervical, Th = thoracic, L = lumbar, S = sacral (degeneration grade according to Thompson)