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  1. Content type: Research

    Low socioeconomic status has been associated with increased morbidity and mortality for various health conditions. The purpose of this study was twofold: to examine the mortality experience of older persons ad...

    Authors: Linda Vrbova, Muhammad Mamdani, Rahim Moineddin, Liisa Jaakimainen and Ross EG Upshur

    Citation: Journal of Negative Results in BioMedicine 2005 4:4

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  2. Content type: Mini-review

    After the introduction of statins in the market as effective lipid lowering agents, they were shown to have effects other than lipid lowering. These actions were collectively referred to as 'pleiotropic action...

    Authors: Nusrat Shafiq, Samir Malhotra, Promila Pandhi and Anil Grover

    Citation: Journal of Negative Results in BioMedicine 2005 4:3

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  3. Content type: Research

    Ghrelin, a peptide secreted by endocrine cells in the gastrointestinal tract, is a hormone purported to have a significant effect on food intake and energy balance in humans. The influence of factors related t...

    Authors: David R Paul, Matthew Kramer, Donna G Rhodes and William V Rumpler

    Citation: Journal of Negative Results in BioMedicine 2005 4:2

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  4. Content type: Research

    Wegener Granulomatosis (WG) is a multifactorial disease of yet unknown aetiology characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis. Analyses of candidate genes revealed ...

    Authors: Peter Jagiello, Stefan Wieczorek, Philipp Yu, Elena Csernok, Wolfgang L Gross and Joerg T Epplen

    Citation: Journal of Negative Results in BioMedicine 2005 4:1

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  5. Content type: Research

    Glycoprotein 210 (GP210) is a transmembrane component of the nuclear pore complex of metazoans, with a short carboxyterminus protruding towards the cytoplasm. Its function is unknown, but it is considered to b...

    Authors: Magnus Olsson, Milton A English, Jacqueline Mason, Jonathan D Licht and Peter Ekblom

    Citation: Journal of Negative Results in BioMedicine 2004 3:7

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  6. Content type: Research

    Disturbances in the immune system has been described in Turner syndrome, with an association to low levels of IgG and IgM and decreased levels of T- and B-lymphocytes. Also different autoimmune diseases have b...

    Authors: Annika E Stenberg, Lisskulla Sylvén, Carl GM Magnusson and Malou Hultcrantz

    Citation: Journal of Negative Results in BioMedicine 2004 3:6

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  7. Content type: Research

    CP-31398 is a small molecule that has been reported to stabilize the DNA-binding core domain of the human tumor suppressor protein p53 in vitro. The compound was also reported to function as a potential anti-canc...

    Authors: Stefan Tanner and Alcide Barberis

    Citation: Journal of Negative Results in BioMedicine 2004 3:5

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  8. Content type: Research

    S100B belongs to a family of calcium-binding proteins implicated in intracellular and extracellular regulatory activities. This study of serum S100B in primary progressive multiple sclerosis (PPMS) is based on...

    Authors: Ee Tuan Lim, Axel Petzold, Siobhan M Leary, Daniel R Altmann, Geoff Keir, Ed J Thompson, David H Miller, Alan J Thompson and Gavin Giovannoni

    Citation: Journal of Negative Results in BioMedicine 2004 3:4

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  9. Content type: Research

    There are no studies investigating the effect of the contrast infusion on the sensitivity and specificity of the main Doppler criteria of renal artery stenosis (RAS). Our aim was to evaluate the accuracy of th...

    Authors: Odila UN Teixeira, Luiz A Bortolotto and Hélio Bernardes Silva

    Citation: Journal of Negative Results in BioMedicine 2004 3:3

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  10. Content type: Brief report

    The engineering of green fluorescent protein (GFP) fusion constructs in order to visibly tag a protein of interest has become a commonly used cell biology technique. Although caveats to this approach are obvio...

    Authors: Dennis A Hanson and Steven F Ziegler

    Citation: Journal of Negative Results in BioMedicine 2004 3:2

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  11. Content type: Research

    Approximately 10 to 20 percent of the population is suffering from chronic pain. Since this represents a major contribution to the costs of the health care system, more efficient measures and interventions to ...

    Authors: Bettina Joos, Daniel Uebelhart, Beat A Michel and Haiko Sprott

    Citation: Journal of Negative Results in BioMedicine 2004 3:1

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  12. Content type: Brief report

    A polymerase chain reaction (PCR)-based method for quantitating CD4 and CD8 mRNA could provide a means of assessing immune status of AIDS patients and other immunologically compromised persons without requirin...

    Authors: Heather B Jaspan, H Richard Gaumer and Robert F Garry

    Citation: Journal of Negative Results in BioMedicine 2003 2:2

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  13. Content type: Research

    Despite extensive progress in determining structures within heparin and heparan sulfate (Hp/HS) and the discovery of numerous proteinaceous binding partners for Hp/HS so far; the only detailed characterization...

    Authors: David E Hoke, Daniel D Carson and Magnus Höök

    Citation: Journal of Negative Results in BioMedicine 2003 2:1

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  14. Content type: Research

    Physicians reading the medical literature attempt to determine whether research studies are valid. However, articles with negative results may not provide sufficient information to allow physicians to properly...

    Authors: Randy S Hebert, Scott M Wright, Robert S Dittus and Tom A Elasy

    Citation: Journal of Negative Results in BioMedicine 2002 1:1

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