Table 2 Association analysis of SNP rs547984 with allele frequency and genotype distribution in POAG patients and controls
SNP (Nearest gene) | rs547984 (ZP4) | ||||
|---|---|---|---|---|---|
Allelic analysis | Controls (n = 95) No. (%) | POAG (n = 90) No. (%) | Odds ratio | 95% confidence interval | p valuea |
C | 95 (50.0) | 92 (51.1) | 1 | Reference | - |
Ab | 95 (50.0) | 88 (48.9) | 1.08 | 0.72 – 1.62 | 0.708 |
HWE P | 0.60 | 0.13 | - | - | - |
Genotype and Model analysis | |||||
C/C | 25 (26.3) | 20 (22.2) | 1 | Reference | - |
C/A | 45 (47.3) | 52 (57.7) | 0.69 | 0.34 – 1.41 | 0.310 |
A/A | 25 (26.3) | 18 (20.0) | 1.11 | 0.47 – 2.58 | 0.806 |
Additive (Trend) | - | - | - | - | 0.356c |
Dominant | - | - | 1.25 | 0.63 – 2.45 | 0.517 |
Recessive | - | - | 0.70 | 0.35 – 1.39 | 0.309 |