Fig. 2From: Do anti-amyloid beta protein antibody cross reactivities confound Alzheimer disease research?Epitopes recognised by commonly used antibodies in various Aβ –type peptides. a fragments associated with the main α- and β- cleavage pathways, b fragments associated with BACE2 catabolism. Note: Aβ can exist as monomers, dimers, oligomers and fibrils; epitopes may be lost due to conformational change due to aggregation/solubility etc.; antibodies do not react with specific Aβ sequences in all conditions; amino acids of epitopes for MBC40 (Aβ40) and MBC42 (Aβ42) not well describedBack to article page