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Fig. 2 | Journal of Negative Results in BioMedicine

Fig. 2

From: Do anti-amyloid beta protein antibody cross reactivities confound Alzheimer disease research?

Fig. 2

Epitopes recognised by commonly used antibodies in various Aβ –type peptides. a fragments associated with the main α- and β- cleavage pathways, b fragments associated with BACE2 catabolism. Note: Aβ can exist as monomers, dimers, oligomers and fibrils; epitopes may be lost due to conformational change due to aggregation/solubility etc.; antibodies do not react with specific Aβ sequences in all conditions; amino acids of epitopes for MBC40 (Aβ40) and MBC42 (Aβ42) not well described

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