Fig. 5
From: Unspecific binding of cRNA probe to plaques in two mouse models for Alzheimer’s disease
a; b; f; g: Results from an attempt to eliminate unspecific plaque binding by using fluorescein-tagged sense (b; c) and antisense (a; f) probes for Pcdh10. c; h: Results from using antisense probes for chicken Pcdh10. d; i: Antisense Pcdh8 staining without formamide in the washing buffers on transgenic and wild-type sections of 6-months-old APP/PS1 mice. e; j: RNase pretreatment of brain sections before standard Pcdh8-in situ hybridization on wild-type and transgenic brain section of 6-months-old APP/PS1. The asterisks in b; d; e; f; g; h; i indicate dissection artifacts (see legend to Fig. 1). tg, transgenic; wt, wild-type. Scale bar in f = 1 mm (applies to all panels)