Dietary phosphate supplement does not rescue skeletal phenotype in a mouse model for craniometaphyseal dysplasia

Table 4 Biochemical analysis of plasma from CMD patients

Case	Ank mutation	Age	Gender	PTH (pg/ml)	25OHD (ng/ml)	i-FGF23 (pg/ml)	c-FGF23 (RU/ml)
1	F377del	45	F	63.14	32.90	13.42	61.85
2	F377del	17	F	37.38	40.92	19.84	59.02
3	F377del	14	F	31.41	34.26	14.64	50.83
4	F377del	9	F	28.78	29.68	13.71	14.25
5	S375del	10	F	35.57	13.4	33.16	31.95
6	S375del	48	F	26.75	18.56	13.51	30.66
7	C331 → R	18	M	16.53	23.82	10.02	63.25

i-FGF23: intact FGF23; c-FGF23: C-terminal form of FGF23; Normal range of human hormones: 1) human PTH: 12–65 pg/ml; 2) human i-FGF23: 10–50 pg/ml; 3) human c-FGF23: <120-150 RU/ml. 4) human vitamin D insufficiency: 21–29 ng/ml; vitamin D deficiency < 20 ng/ml. Bold number indicated cases with vitamin D insufficiency or deficiency

ISSN: 1477-5751