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Table 3 Effect of genotypes on demographic and other clinical characteristics among POAG cases

From: Polymorphism rs7555523 in transmembrane and coiled-coil domain 1 (TMCO1) is not a risk factor for primary open angle glaucoma in a Saudi cohort

Variables

Category

Genotypes

p value

A/A

(N = 69)

No. (%)

A/C

(N = 18)

No. (%)

Demographic Characteristics

 Age in years, Mean (±SD)

-

61.5 (13.2)

59.8 (9.9)

0.644

 Gender

Male

43 (62.3)

9 (50.0)

0.4212

Female

26 (37.7)

9 (50.0)

-

Systemic Diseases

 Diabetes mellitus

Present

37 (53.6)

6 (33.3)

0.205

 Hypertension

Present

34 (49.3)

8 (44.4)

0.920

 Coronary artery disease

Present

4 (5.8)

1 (5.6)

0.971

 Hypercholesterolemia

Present

9 (13.0)

4 (22.2)

0.357

Health Awareness / Behavior

 Family history of glaucoma

Yes

9 (13)

2 (11.1)

0.988

 Smoking

Yes

26 (38.2)

10 (55.6)

0.272

 Awareness to glaucoma

Yes

14 (20.3)

0.0 (0.0)

0.036

Glaucoma Specific Indices

 Intraocular pressure in mmHg, Mean (±SD)

-

35.0 (7.5)

34.8 (8.0)

0.778

 Cup/disc ratio, Mean (±SD)

-

0.72 (0.18)

0.7 (0.2)

0.740

 Number of anti-glaucoma medications, Mean (±SD)

-

2.9 (0.7)

2.8 (0.6)

0.765