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Table 1 Baseline characteristics of all patients with traumatic brain injury taking OAC

From: Age is not associated with intracranial haemorrhage in patients with mild traumatic brain injury and oral anticoagulation

Parameter

OAC

DOAC

Phenprocoumon

n = 260

n = 19

n = 241

Age (years)

79.0 ± 11.3

73.7 ± 13.4

79.7 ± 11.1

Gender (male; female)

67 (25.8 %); 193 (74.2 %)

10 (52.6 %); 9 (47.4 %)

57 (23.7 %); 184 (76.3 %)

Indication

   

 Atrial fibrillation

130 (50.0 %)

8 (42.1 %)

122 (50.6 %)

 Thromboembolic event

71 (27.3 %)

9 (47.4 %)

62 (25.7 %)

 Prophylaxis post-surgery

2 (0.8 %)

2 (10.5 %)

0 (0 %)

 Mechanical heart valve

16 (6.2 %)

0 (0 %)

16 (6.6 %)

 Indication unclear

41 (15.8 %)

0 (0 %)

41 (17.0 %)

Additional medication

   

 Acetylsalicylic acid

16 (6.2 %)

1 (5.3 %)

15 (6.2 %)

 Clopidogrel

8 (3.1 %)

2 (10.5 %)

6 (2.5 %)

Intracranial haemorrhage general

138 (53.1 %)

7 (36.8 %)

131 (54.4 %)

 Epidural bleeding

9 (3.5 %)

0 (0 %)

9 (3.7 %)

 Subdural bleeding

89 (34.2 %)

1 (5.3 %)

88 (36.5 %)

 Subarachnoidal bleeding

39 (15.0 %)

3 (15.8 %)

36 (14.9 %)

 Intracerebral bleeding

34 (13.1 %)

3 (15.8 %)

31 (12.9 %)

  1. Definitions: Oral anticoagulation (OAC) = medication with phenprocoumon or direct oral anticoagulation (DOAC) with rivaroxaban, apixaban or dabigatran
  2. Mean ± Standard deviation or absolute numbers (%)