Table 2 Histological evaluation of inner ears (%, *p < 0.05)
From: Noise trauma and systemic application of the selective glucocorticoid receptor modulator compound A
| Â | Control | CpdA 1Â mg/kg | CpdA 3Â mg/kg | Dex 1Â mg/kg |
|---|---|---|---|---|
Strial detachment 3rd turn* | 2/5 (40Â %) | 1/5 (20Â %) | 6/7 (86Â %) | 0/4 (0Â %) |
Pigmented spiral ligament* | 3/5 (60Â %) | 2/5 (40Â %) | 6/7 (86Â %) | 0/4 (0Â %) |
Pyknotic fibrocytes type III | ||||
Apical 2nd turn and above Basal 2nd turn and above | 2/5 (40Â %) 0/5 (0Â %) | 4/5 (80Â %) 1/5 (20Â %) | 5/7 (71Â %) 2/7 (29Â %) | 2/4 (50Â %) 0/5 (0Â %) |