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Table 5 mRNA expression of prohypertrophic mediators 3 days after onset of aortic constriction in male wild type and Tlr2 deficient mice

From: Tlr2 deficiency does not limit the development of left ventricular hypertrophy in a model of transverse aortic constriction induced pressure overload

 

WT sham

WT TAC

Tlr2−/− sham

Tlr2−/− TAC

TGFβ

1.00 ± 0.04

1.16 ± 0.08

0.93 ± 0.07

1.13 ± 0.05

ANP

1.00 ± 0.27

2.83 ± 0.38

2.16 ± 0.41

3.09 ± 0.49

BNP

1.00 ± 0.19

6.04 ± 1.78*

1.82 ± 0.22

4.41 ± 0.49

  1. mRNA values are normalized to wild type sham group. Mean ± SEM, n = 3–4/sham group, n = 5–8/TAC group. Significant differences (p < 0.05, One-way ANOVA with Sidak post-hoc testing) between relevant groups are indicated (*)
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Journal of Negative Results in BioMedicine

ISSN: 1477-5751

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