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Table 5 mRNA expression of prohypertrophic mediators 3 days after onset of aortic constriction in male wild type and Tlr2 deficient mice

From: Tlr2 deficiency does not limit the development of left ventricular hypertrophy in a model of transverse aortic constriction induced pressure overload

 WT shamWT TACTlr2−/− shamTlr2−/− TAC
TGFβ1.00 ± 0.041.16 ± 0.080.93 ± 0.071.13 ± 0.05
ANP1.00 ± 0.272.83 ± 0.382.16 ± 0.413.09 ± 0.49
BNP1.00 ± 0.196.04 ± 1.78* 1.82 ± 0.224.41 ± 0.49
  1. mRNA values are normalized to wild type sham group. Mean ± SEM, n = 3–4/sham group, n = 5–8/TAC group. Significant differences (p < 0.05, One-way ANOVA with Sidak post-hoc testing) between relevant groups are indicated (*)
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Journal of Negative Results in BioMedicine

ISSN: 1477-5751

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