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Table 4 mRNA and protein expression of pro-inflammatory cytokines 3 days after aortic constriction in male wild type and Tlr2 deficient mice

From: Tlr2 deficiency does not limit the development of left ventricular hypertrophy in a model of transverse aortic constriction induced pressure overload

 WT shamWT TACTlr2−/− shamTlr2−/− TAC
TNFα1.00 ± 0.101.45 ± 0.150.90 ± 0.141.21 ± 0.26
IL-1β1.00 ± 0.282.21 ± 0.521.19 ± 0.421.43 ± 0.21
IL-61.00 ± 0.245.33 ± 0.970.65 ± 0.125.74 ± 1.13*
IL-1β protein1.46 ± 0.253.03 ± 0.531.53 ± 0.192.65 ± 0.44
IL-6 protein15.84 ± 3.8119.94 ± 3.6813.14 ± 2.3122.42 ± 2.63
  1. mRNA values are normalized to the respective sham group. Protein amount in pg/mg protein. Mean ± SEM, n = 3–4/sham group, n = 5–8/TAC group
  2. *indicates significant difference to respective sham group (p < 0.05, One-way ANOVA with Sidak post-hoc testing)
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