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Table 2 Pattern recognition receptor mRNA expression profile 14 days after aortic constriction in male wild type and Tlr2 deficient mice

From: Tlr2 deficiency does not limit the development of left ventricular hypertrophy in a model of transverse aortic constriction induced pressure overload

 

WT sham

WT TAC

Tlr2−/− sham

Tlr2−/− TAC

TLR1

1.00 ± 0.12

1.92 ± 0.25*

0.92 ± 0.19

1.68 ± 0.10*

TLR4

1.00 ± 0.06

1.31 ± 0.11

1.05 ± 0.07

1.59 ± 0.16*

TLR6

1.00 ± 0.09

1.28 ± 0.12

1.28 ± 0.13

1.50 ± 0.08

TLR9

1.00 ± 0.09

1.54 ± 0.22

1.07 ± 0.07

1.55 ± 0.10

CD14

1.00 ± 0.08

1.49 ± 0.19

0.98 ± 0.19

1.57 ± 0.23

  1. Values are normalized to wild type sham group, mean ± SEM, n = 8/group
  2. *indicates significant differences to respective sham group (p < 0.05, One-way ANOVA with Sidak post-hoc testing)
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Journal of Negative Results in BioMedicine

ISSN: 1477-5751

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