Fig. 4

Increased hypertrophy development in Tlr2 ^−/− mice was not gender specific. Comparative analysis of biometric (a, b) and hemodynamic differences (c) after 14 and 28 days of aortic constriction in female Tlr2 ^+/+ and Tlr2 ^−/− mice demonstrated, that Tlr2 ^−/− females also developed more pronounced hypertrophy than WT mice (mean ± SEM, One-way ANOVA with Tukey post-hoc testing, n = 7–11/group)