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Figure 4 | Journal of Negative Results in BioMedicine

Figure 4

From: Shortcomings of short hairpin RNA-based transgenic RNA interference in mouse oocytes

Figure 4

Characterization of transgenic animals. (A) EGFP expression in brain, tail and kidney of transgenic animals. Bright-field images are shown to illustrate organ morphology. F1 generation mice from all transgenic lines were used for the analysis. EGFP expression in transgenic mice carrying a CMV-EGFP transgene (P.S., unpublished results) is shown for comparison. (B) EGFP expression in oocytes isolated form wild-type and transgenic animals. Bright-field images are shown to illustrate oocyte morphology. (C) EGFP expression in primary fibroblast isolated from wild-type and transgenic animals. NIH3T3 cells transfected with pZMP plasmid were used as positive controls.

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