Human haematopoietic stem cells express Oct4 pseudogenes and lack the ability to initiate Oct4 promoter-driven gene expression

Table 1 Summary of Oct4 sequencing data.

	Oct4 Chromosome 6	Pseudogene Chromosome 1	Pseudogene Chromosome 10	Pseudogene Chromosome 12
C-kit+ T0	No	Yes	Yes	-
C-Kit+ T7	No	-	Yes	Yes
EC 2102Ep	Yes	-	-	-
Hek293T	No	-	-	Yes
HepG2	No	Yes	-	-

Expression of Oct4 was observed in EC 2102Ep cells (+ control). All other cells expressed a variety of Oct4 pseudogene transcripts derived from chromosomes 1, 10 and 12. C-kit⁺ cells (T0) n = 7, c-kit⁺ cells (T7) n = 4, all other cell types n = 3.

ISSN: 1477-5751