Figure 2From: Oxaliplatin neurotoxicity – no general ion channel surface-charge effectShaker wild-type channel. Oxaliplatin does not affect the Shaker wild-type channel. A) Current family in control solution. Voltage steps between -80 mV and 0 mV in steps of 10 mV. Holding voltage = -80 mV. Time between each step is 2 s. Recordings done by the two-electrode voltage clamp technique. B) Current family with 240 μM oxaliplatin added to the extracellular solution. C) Conductance versus voltage curve for the data from A and B.Back to article page