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Table 2 Clinical characteristics of family 310. The patient number refers to the number in the pedigree in Figure 1.

From: PALB2 variants in hereditary and unselected Finnish Prostate cancer cases

Patient Cancer Histology Age at diagnosis Reason for diagnosis First treatment Primary PSA value WHO grading Gleason grading TNM grading IHC
6 Prostate Adenocarcinoma 83 NA NA NA NA NA NA  
11 Prostate Adenocarcinoma 68 Symptoms Orchiectomy NA III Na T3NXMX  
13 Stomach Adenocarcinoma 70 Symptoms Gastrectomy NA NA Na T4N0 M0  
13 Skin Carcinoma epidermoides 75 NA Resection NA NA Na NA  
13 Prostate Adenocarcinoma 76 Elevated PSA Orchiectomy 47 III 2+3 = 5 T2NXMX  
15 Prostate Adenocarcinoma 69 Elevated PSA Brakytherapy 7.7 I 2+3 = 5 T1cNXMX  
17 Breast Ductal carcinoma 52 Screening mammography Mammary resection NA I Na T1N0 M0 ER+, PR+
24 Breast Ductal carcinoma 49 Mammography Mammary resection NA I Na T1N0 M0 NA
  1. IHC = immunohistochemistry, NA = not available