Table 2 Genotype frequencies of EDN, ECP, EPO and MBP polymorphisms in AD patients and controls.
From: Variation in genes encoding eosinophil granule proteins in atopic dermatitis patients from Germany
Gene | Polymorphism | Genotypes | AD patients | controls | p-value |
|---|---|---|---|---|---|
EDN | rs2013109 | C/C | 22 (6.1%) | 23 (7.1%) | 0.66 |
C/G | 148 (41.0%) | 123 (37.8%) | |||
G/G | 191 (52.9%) | 179 (55.1%) | |||
rs10132319 | Not polymorphic | - | - | - | |
ECP | rs2073342 | A/A | 53 (14.7%) | 57 (17.6%) | 0.45 |
A/C | 185 (51.2%) | 152 (47.1%) | |||
C/C | 123 (34.1%) | 114 (35.3%) | |||
rs2073342 | C/C | 26 (7.2%) | 32 (9.8%) | 0.13 | |
C/G | 158 (43.9%) | 120 (36.9%) | |||
G/G | 176 (48.9%) | 173 (53.2%) | |||
rs2233860 | C/C | 15 (4.1%) | 19 (5.9%) | 0.55 | |
C/G | 123 (34.1%) | 104 (32.1%) | |||
G/G | 223 (61.8%) | 201 (62.0%) | |||
EPO | rs11652709 | C/C | 34 (9.4%) | 35 (10.8%) | 0.42 |
C/G | 170 (47.2%) | 137 (42.3%) | |||
G/G | 156 (43.3%) | 152 (46.9%) | |||
rs3785496 | G/G | 23 (6.4%) | 18 (5.6%) | 0.89 | |
G/A | 142 (39.4%) | 130 (40.1%) | |||
A/A | 195 (54.2%) | 176 (54.3%) | |||
MBP | rs490358 | A/A | 29 (8.0%) | 27 (8.3%) | 0.98 |
A/G | 137 (38.0%) | 121 (37.2%) | |||
G/G | 195 (54.0%) | 177 (54.5%) | |||
rs3741089 | T/T | 99 (27.6%) | 99 (30.7%) | 0.66 | |
T/C | 184 (51.2%) | 158 (49.1%) | |||
C/C | 76 (21.2%) | 65 (20.2%) |