From: Tolerance and rebound with zafirlukast in patients with persistent asthma
Zafirlukast (n = 9) | Placebo (n = 11) | |||
---|---|---|---|---|
Baseline | 12 weeks | Baseline | 12 weeks | |
*TCC × 10 3 /ml | 38.8 (0.6–293.8) | 22.8 (0.3–93.8) | 41.0 (0.5–176) | 41.5 (3.8–109.3) |
Sputum eosinophils, % | 5.8 (0.8–39.2) | 4.0 (0.4–54.6) | 5.3 (0.2–14.7) | 1.7 (0–39.5) |
CysLT pg/ml | 331 (182–648) | 567 (151–1029) | 192 (15–763) | 412 (49–1332) |
PGE 2 pg/ml | 942 (572–1951) | 1276 (836–2513) | 1245 (479–6155) | 959.2 (329–3756) |