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Table 1 Demographics of investigated groups

From: No evidence of enhanced oxidant production in blood obtained from patients with obstructive sleep apnea

 

Subjects that underwent polysomnography

Parameter

OSAS group, n = 27

Severe OSAS subgroup, n = 11

CPAP-OSAS group, n= 22

Controls, n = 11

Male/Female

25/2

10/1

17/5

9/3

Smokers

15

0

15

6

Age [yrs]

53 ± 13

55 ± 15

58 ± 8

50 ± 10

BMI [kg/m2]

31.1 ± 5.1

32.1 ± 6.5

34.3 ± 7.3

28.8 ± 5.5

NC [cm]

42.6 ± 2.6

43.7 ± 2.9

43.7 ± 4.1

41.5 ± 2.0

ESS

11 ± 1

11 ± 5

15 ± 1*

9 ± 1

TST [h]

4.8 ± 1.2

4.7 ± 1.3

5.2 ± 1.6

5.3 ± 1.0

AHI [n/h]

31 ± 5

58 ± 18 †

9 ± 2*

2 ± 1*

ODI [n/h]

31 ± 5

55 ± 19 †

9 ± 3*

2 ± 1*

Mean SaO2 [%]

87 ± 1

84 ± 5 †

89 ± 1

91 ± 1*

Min SaO2 [%]

74 ± 3

68 ± 15 †

81 ± 2

88 ± 1*

TSaO2<88% [min]

55 ± 12

99 ± 74 †

12 ± 4*

2 ± 1*

Snoring [%TST]

29 ± 24

28 ± 24

10 ± 14*

20 ± 25

  1. OSAS – patients with untreated OSAS; Severe OSAS – patients with AHI ≥ 30; CPAP-OSAS – patients with OSAS treated successfully at a first attempt with CPAP, controls – subjects without OSAS; BMI – body mass index; NC – neck circumference; ESS – Epworth sleepiness score; TST – total sleep time; AHI (apnea/hypopnea index) – the number of apneas and hypopneas per hour of sleep; ODI (oxygen desaturation index) – the number of desaturations ≥ 4% per hour of sleep; SaO2-nocturnal oxygen saturation; TSaO2 – duration of nocturnal oxygen saturation < 88%. Polysomnography data expressed as a mean ± SD. The daily cigarette consumption was 19 ± 12, 21 ± 13, and 17 ± 6 for current cigarette smokers in OSAS, CPAP-OSAS and control groups respectively. Blood for chemiluminescence measurement and other determinations was taken before and after polysomnographic controlled sleep.
  2. * – p < 0.05 vs. OSAS group, † – p < 0.05 vs. CPAP-OSAS and controls groups.
  3. Selected baseline characteristics of CPAP-OSAS patients before treatment initiation were: AHI 58 ± 29; ODI 56 ± 26; mean SaO2 82 ± 7 %, min SaO2 75 ± 9 %, and TSaO2 < 88% 105 ± 90 min. of 5.2 ± 1.7 h TST.