| |
Subjects that underwent polysomnography
|
|---|
|
Parameter
|
OSAS group, n = 27
|
Severe OSAS subgroup, n = 11
|
CPAP-OSAS group, n= 22
|
Controls, n = 11
|
|
Male/Female
|
25/2
|
10/1
|
17/5
|
9/3
|
|
Smokers
|
15
|
0
|
15
|
6
|
|
Age [yrs]
|
53 ± 13
|
55 ± 15
|
58 ± 8
|
50 ± 10
|
|
BMI [kg/m2]
|
31.1 ± 5.1
|
32.1 ± 6.5
|
34.3 ± 7.3
|
28.8 ± 5.5
|
|
NC [cm]
|
42.6 ± 2.6
|
43.7 ± 2.9
|
43.7 ± 4.1
|
41.5 ± 2.0
|
|
ESS
|
11 ± 1
|
11 ± 5
|
15 ± 1*
|
9 ± 1
|
|
TST [h]
|
4.8 ± 1.2
|
4.7 ± 1.3
|
5.2 ± 1.6
|
5.3 ± 1.0
|
|
AHI [n/h]
|
31 ± 5
|
58 ± 18 †
|
9 ± 2*
|
2 ± 1*
|
|
ODI [n/h]
|
31 ± 5
|
55 ± 19 †
|
9 ± 3*
|
2 ± 1*
|
|
Mean SaO2 [%]
|
87 ± 1
|
84 ± 5 †
|
89 ± 1
|
91 ± 1*
|
|
Min SaO2 [%]
|
74 ± 3
|
68 ± 15 †
|
81 ± 2
|
88 ± 1*
|
|
TSaO2<88% [min]
|
55 ± 12
|
99 ± 74 †
|
12 ± 4*
|
2 ± 1*
|
|
Snoring [%TST]
|
29 ± 24
|
28 ± 24
|
10 ± 14*
|
20 ± 25
|
- OSAS – patients with untreated OSAS; Severe OSAS – patients with AHI ≥ 30; CPAP-OSAS – patients with OSAS treated successfully at a first attempt with CPAP, controls – subjects without OSAS; BMI – body mass index; NC – neck circumference; ESS – Epworth sleepiness score; TST – total sleep time; AHI (apnea/hypopnea index) – the number of apneas and hypopneas per hour of sleep; ODI (oxygen desaturation index) – the number of desaturations ≥ 4% per hour of sleep; SaO2-nocturnal oxygen saturation; TSaO2 – duration of nocturnal oxygen saturation < 88%. Polysomnography data expressed as a mean ± SD. The daily cigarette consumption was 19 ± 12, 21 ± 13, and 17 ± 6 for current cigarette smokers in OSAS, CPAP-OSAS and control groups respectively. Blood for chemiluminescence measurement and other determinations was taken before and after polysomnographic controlled sleep.
- * – p < 0.05 vs. OSAS group, † – p < 0.05 vs. CPAP-OSAS and controls groups.
- Selected baseline characteristics of CPAP-OSAS patients before treatment initiation were: AHI 58 ± 29; ODI 56 ± 26; mean SaO2 82 ± 7 %, min SaO2 75 ± 9 %, and TSaO2 < 88% 105 ± 90 min. of 5.2 ± 1.7 h TST.
