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Table 1 Demographics of investigated groups

From: No evidence of enhanced oxidant production in blood obtained from patients with obstructive sleep apnea

  Subjects that underwent polysomnography
Parameter OSAS group, n = 27 Severe OSAS subgroup, n = 11 CPAP-OSAS group, n= 22 Controls, n = 11
Male/Female 25/2 10/1 17/5 9/3
Smokers 15 0 15 6
Age [yrs] 53 ± 13 55 ± 15 58 ± 8 50 ± 10
BMI [kg/m2] 31.1 ± 5.1 32.1 ± 6.5 34.3 ± 7.3 28.8 ± 5.5
NC [cm] 42.6 ± 2.6 43.7 ± 2.9 43.7 ± 4.1 41.5 ± 2.0
ESS 11 ± 1 11 ± 5 15 ± 1* 9 ± 1
TST [h] 4.8 ± 1.2 4.7 ± 1.3 5.2 ± 1.6 5.3 ± 1.0
AHI [n/h] 31 ± 5 58 ± 18 † 9 ± 2* 2 ± 1*
ODI [n/h] 31 ± 5 55 ± 19 † 9 ± 3* 2 ± 1*
Mean SaO2 [%] 87 ± 1 84 ± 5 † 89 ± 1 91 ± 1*
Min SaO2 [%] 74 ± 3 68 ± 15 † 81 ± 2 88 ± 1*
TSaO2<88% [min] 55 ± 12 99 ± 74 † 12 ± 4* 2 ± 1*
Snoring [%TST] 29 ± 24 28 ± 24 10 ± 14* 20 ± 25
  1. OSAS – patients with untreated OSAS; Severe OSAS – patients with AHI ≥ 30; CPAP-OSAS – patients with OSAS treated successfully at a first attempt with CPAP, controls – subjects without OSAS; BMI – body mass index; NC – neck circumference; ESS – Epworth sleepiness score; TST – total sleep time; AHI (apnea/hypopnea index) – the number of apneas and hypopneas per hour of sleep; ODI (oxygen desaturation index) – the number of desaturations ≥ 4% per hour of sleep; SaO2-nocturnal oxygen saturation; TSaO2 – duration of nocturnal oxygen saturation < 88%. Polysomnography data expressed as a mean ± SD. The daily cigarette consumption was 19 ± 12, 21 ± 13, and 17 ± 6 for current cigarette smokers in OSAS, CPAP-OSAS and control groups respectively. Blood for chemiluminescence measurement and other determinations was taken before and after polysomnographic controlled sleep.
  2. * – p < 0.05 vs. OSAS group, † – p < 0.05 vs. CPAP-OSAS and controls groups.
  3. Selected baseline characteristics of CPAP-OSAS patients before treatment initiation were: AHI 58 ± 29; ODI 56 ± 26; mean SaO2 82 ± 7 %, min SaO2 75 ± 9 %, and TSaO2 < 88% 105 ± 90 min. of 5.2 ± 1.7 h TST.