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Figure 3 | Journal of Negative Results in BioMedicine

Figure 3

From: VEGF receptors on PC12 cells mediate transient activation of ERK1/2 and Akt: comparison of nerve growth factor and vascular endothelial growth factor

Figure 3

Western blot analyses of VEGF-induced signal transduction in differentiated PC12 cells after NGF withdrawal. Lysates of control cells maintained in the presence of NGF were loaded in lane 1. NGF-deprived PC12 cells (lane 2) treated with VEGF165 (lanes 3, 4) or NGF (lanes 5, 6) demonstrated that VEGF165 induced transient activation of ERK1/2 and Akt after 7 min. In contrast, NGF produced a stronger and persistent phosphorylation of ERK1/2 and Akt than VEGF165.

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