Table 2 Genotype distribution of the PLIN rs4578621 and rs894160 SNP according to BMI categories and diabetes status
From: Study of the impact of perilipin polymorphisms in a French population
rs4578621 | rs894160 | ||||||
|---|---|---|---|---|---|---|---|
CC | CG+GG | p | GG | GA | AA | p | |
Men | Men | ||||||
BMI<25 kg/m2 (228) | 194 (85.1) | 34 (14.9) | 109 (47.8) | 97 (42.5) | 22 (9.7) | ||
25≤BMI<30 kg/m2 (238) | 204 (85.7) | 34 (14.3) | ns | 113 (47.5) | 103 (43.3) | 22 (9.2) | ns |
BMI≥30 kg/m2 (104) | 91 (87.5) | 13 (12.5) | 58 (55.8) | 36 (34.6) | 10 (9.6) | ||
Non-diabetic (397) | 337 (84.9) | 60 (15.1) | 186 (46.9) | 168 (42.3) | 43 (10.8) | ||
Diabetic (151 M/160 W) | 127 (84.1) | 24 (15.9) | ns | 82 (51.3) | 62 (38.7) | 16 (10.0) | ns |
Women | Women | ||||||
BMI<25 kg/m2 (249) | 216 (86.8) | 33 (13.2) | 129 (51.8) | 97 (39.0) | 23 (9.2) | ||
25≤BMI<30 kg/m2 (172) | 145 (84.3) | 27 (15.7) | ns | 87 (50.6) | 79(45.9) | 6 (3.5) | ns |
BMI≥30 kg/m2 (123) | 103 (83.7) | 20 (16.3) | 58 (47.2) | 54 (43.9) | 11 (8.9) | ||
Non-diabetic (439) | 382 (87.0) | 57 (13.0) | 220 (50.1) | 188 (42.8) | 31 (7.1) | ||
Diabetic (108 M/115 W) | 91 (84.3) | 17 (15.7) | ns | 66 (57.4) | 39 (33.9) | 10 (8.7) | ns |