Table 1 Genes investigated for CD association as represented by an intra- or juxtagenic microsatellite marker (for additional information see URL: http://www.ruhr-uni-bochum.de/mhg/marker_information_SENW.pdf)
apoptosis related | REQ | TNFSF12 | CTLA4 | Casp10 | IL4 |
|---|---|---|---|---|---|
RNF7 | TNFSF14 | DAP | Casp14 | IL4R | |
SMAC | TNFSF15 | DAPK1 | Casp2 | IL6 | |
AIF | TIAF1 | TNFSF18 | FADD | Casp3 | IL8 |
APR3 | TIAL1 | TNFSF4 | IKBKG | Casp4 | IRF1 |
BCLG | TP73 | TNFSF5 | MADD | Casp5 | NRG1B |
BFAR | VDR | TNFSF6 | MAP2K6 | Casp6 | PRL |
CIDEB | TNFSF7 | MAP3K14 | Casp7 | PRLR | |
CYBB | Bcl2 related | TNFSF8 | MAP3K5 | Casp8 | |
CYP51 | TNFSF9 | MAP4K4 | CASP8AP2 | chromosome 6 | |
DAD1 | BCL2A1 | TOSO | NFKB1 | Casp9 | |
DAP3 | Bag1 | NFKB2 | No.1 | ||
DATF1 | BAK | innate immunity | NSMAF | apoptosis suppressor | No.4 |
DAXX | BAX | PAWR | No.5 | ||
DEDD | BCL2 | BPI | PIAS3 | No.6 | |
DHCR24 | BCL2L1 | CD14 | PTEN | API5 | No.7 |
EIF4G2 | BCL2L11 | CD5L | RARB | BIRC1 | No.8 |
FASTK | BCL2L13 | DEFB119/ DEFB121 | RIPK1 | BIRC2 | D6S1014 |
FLIP | BID | DEFB127 | RIPK2 | BIRC3 | D6S1959 |
FRZB | BIK | HBD1 | RIPK3 | BIRC4 | D6S273 |
GSK3B | BNIP3L | IFNB1 | RXRB | BIRC6 | |
GSR | MCL1 | LY64 | STK17A | BIRC8 | others |
GZMA | LY86 | STK17B | |||
GZMB | TNF superfamily | LY96 | TANK | cytokine chemokines | BPHL/TUBB |
HLCS | NCF1 | TRADD | TAPBPR | ||
NME3 | LTB (TNFSF3) | NCF4 | Traf3 | VEGF | |
NOL3 | LTBR (TNFRSF3) | PGLYRP | Traf4 | AXL | LGALS3 |
NOS1 | TNFa | PLA2G4A | Traf5 | CSF1R | BDNF |
NOS2A | TNFRSF10A | PLUNC | Traf6 | CSF2 | NGFB |
NOX1 | TNFRSF10B | SerpinA1 | CSF2RB | NGFR | |
NOX3 | TNFRSF10C | SerpinB1 | cell cycle regulators | CSF3 | TrkC |
NOX4 | TNFRSF10D | SFTPA1 | Dtk | ||
P2RX1 | TNFRSF11A | SLPI | CCND2 | erbB3 | positive control |
P53AIP1 | TNFRSF11B | STAT3 | CDC2 | GAS1 | CARD15 |
PDCD10 | TNFRSF12 | TGFB1 | CDKN1A | IGF1 | |
PDCD2 | TNFRSF17 | TLR1 | CDKN2A | IGF2R | |
PDCD5 | TNFRSF18 | TLR2 | PAK1B | IL10 | |
PDCD6 | TNFRSF19 | TLR3 | RbAp48 | IL10RA | |
PDCD6IP | TNFRSF19L | TLR4 | Rb2/p130 | IL10RB | |
PDCD8 | TNFRSF1A | TLR5 | RBP1 | IL11RA | |
PLA2G10 | TNFRSF1B | TLR7 | RBP2 | IL12A | |
PLA2G1B | TNFRSF21 | TLR8 | RBQ-1 | IL12B | |
PLA2G6 | TNFRSF4 | TLR9 | RBQ-3 | IL12RB2 | |
PTGS1 | TNFRSF5 | TLR10 | TP53 | IL13RA2 | |
REQ | TNFRSF6 (FAS) | TP53INP1 | IL18 | ||
RNF7 | TNFRSF6B | signal transduction | IL18R | ||
SMAC | TNFRSF7 | caspase related | IL1RL1 | ||
TIAF1 | TNFRSF8 | Traf1 | IL1B | ||
TIAL1 | TNFRSF9 | BCL10 | ADPRT | IL2 | |
TP73 | TNFSF10 | CHUK | CARD4 | IL24 | |
VDR | TNFSF11 | CRADD | Casp1 | IL2RA |