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Table 1 Number of different genotype combinations of the MTHFR 677C→Ta and 1298 A→Cb polymorphism in 167 HD patients

From: Failure to confirm influence of Methyltetrahydrofolate reductase (MTHFR) polymorphisms on age at onset of Huntington disease

MTHFR

677CC (%)

677CT (%)

677TT (%)

genotype

n = 71

n = 75

n = 21

1298AA (n = 80)

23 (13.7)

37 (22.1)

20 (12)

1298AC (n = 74)

35 (21)

38 (22.8)

1 (0.6)

1298CC(n = 13)

13(7.8)

0

0

  1. aAllele frequency of MTHFR 677T amounts to 0.35.
  2. bAllele frequency of MTHFR 1298C amounts to 0.29.