| |
N cases
|
Overall Breast cancer
|
N casesa
|
ER+/ PR+
|
N casesa
|
ER+/ PR-
|
N casesa
|
ER-/PR-
|
|---|
|
Changes in PA levelb
| | | |
RR (95% CI)c
| |
RR (95% CI)c
| |
RR (95% CI)c
|
|---|
|
Age 14 to age 30
| | | | | | | | |
|
Inactive
|
75
|
0.78 (0.62, 0.99)
|
37
|
0.79 (0.56, 1.10)
|
9
|
0.53 (0.27, 1.03)
|
10
|
0.91 (0.48, 1.73)
|
|
Active to inactive
|
163
|
1.18 (1.0, 1.39)
|
96
|
1.43 (1.15, 1.78)
|
27
|
1.10 (0.74, 1.65)
|
11
|
0.72 (0.39, 1.32)
|
|
Inactive to active
|
125
|
0.81 (0.67,0 .97)
|
56
|
0.74 (0.56, 0.97)
|
20
|
0.73 (0.46, 1.15)
|
21
|
1.16 (0.73. 1.82)
|
|
Active
|
1334
|
1.0 ref
|
650
|
1.0 ref
|
229
|
1.0 ref
|
155
|
1.0 ref
|
|
Age 14 to enrollment
| | | | | | | | |
|
Inactive
|
72
|
0.82 (0.64, 1.03)
|
34
|
0.75 (0.53, 1.06)
|
9
|
0.63 (0.32, 1.24)
|
10
|
1.06 (0.56, 2.03)
|
|
Active to inactive
|
419
|
1.06 (0.95, 1.20)
|
203
|
1.00 (0.85, 1.18)
|
78
|
1.29 (0.98, 1.69)
|
44
|
1.07 (0.75, 1.52)
|
|
Inactive to active
|
130
|
0.79 (.66, 0.95)
|
59
|
0.71 (0.54, 0.93)
|
20
|
0.71 (0.45, 1.13)
|
21
|
1.12 (0.70, 1.77)
|
|
Active
|
1091
|
1.0 ref
|
550
|
1.0 ref
|
179
|
1.0 ref
|
124
|
1.0 ref
|
|
Age 30 to enrollment
| | | | | | | | |
|
Inactive
|
146
|
1.06 (0.89, 1.27)
|
79
|
1.15 (0.91, 1.46)
|
24
|
1.05 (0.69, 1.62)
|
11
|
0.72 (0.39, 1.33)
|
|
Active to inactive
|
347
|
1.04 (0.92, 1.18)
|
160
|
0.95 (0.79, 1.13)
|
64
|
1.27 (0.95, 1.69)
|
43
|
1.18 (0.83, 1.67)
|
|
Inactive to active
|
94
|
1.01 (0.82, 1.25)
|
55
|
1.19 (0.90, 1.57)
|
12
|
0.77 (0.43, 1.37)
|
11
|
1.01 (0.54, 1.87)
|
|
Active
|
1136
|
1.0 ref
|
562
|
1.0 ref
|
188
|
1.0 ref
|
136
|
1.0 ref
|
-
aThe total number of breast cancer does not add up caused by missing information on PA at younger ages, age 14 to age 30 n = 77,272, age 14 to enrollment n = 77,623 and age 30 to enrollment n = 78,477.
-
bInactive: very low or low PA level, Active: moderate, high or very high PA level.
-
cThe multivariable model with RR and 95% CI used the attained age as the underlying time variable. Covariates adjusted for in the model were height, body mass index, smoking status, duration of smoking (pack years), age at smoking initiation, age at menarche, use of oral contraceptives, age at first birth, parity, use of hormone replacement therapy, self-reported disease and history of breast cancer in the participant’s mother.
- RR: relative risks; CI: confidence intervals.
