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Table 5 Postmenopausal breast cancer risk overall and by estrogen receptor (ER) and progesterone receptor (PR) status of breast tumors and changes in physical activity (PA) level among 1,767 breast cancer cases in the Norwegian Women and Cancer Study

From: Physical activity and the risk of postmenopausal breast cancer - the Norwegian Women and Cancer Study

 

N cases

Overall Breast cancer

N casesa

ER+/ PR+

N casesa

ER+/ PR-

N casesa

ER-/PR-

Changes in PA levelb

   

RR (95% CI)c

 

RR (95% CI)c

 

RR (95% CI)c

Age 14 to age 30

        

Inactive

75

0.78 (0.62, 0.99)

37

0.79 (0.56, 1.10)

9

0.53 (0.27, 1.03)

10

0.91 (0.48, 1.73)

Active to inactive

163

1.18 (1.0, 1.39)

96

1.43 (1.15, 1.78)

27

1.10 (0.74, 1.65)

11

0.72 (0.39, 1.32)

Inactive to active

125

0.81 (0.67,0 .97)

56

0.74 (0.56, 0.97)

20

0.73 (0.46, 1.15)

21

1.16 (0.73. 1.82)

Active

1334

1.0 ref

650

1.0 ref

229

1.0 ref

155

1.0 ref

Age 14 to enrollment

        

Inactive

72

0.82 (0.64, 1.03)

34

0.75 (0.53, 1.06)

9

0.63 (0.32, 1.24)

10

1.06 (0.56, 2.03)

Active to inactive

419

1.06 (0.95, 1.20)

203

1.00 (0.85, 1.18)

78

1.29 (0.98, 1.69)

44

1.07 (0.75, 1.52)

Inactive to active

130

0.79 (.66, 0.95)

59

0.71 (0.54, 0.93)

20

0.71 (0.45, 1.13)

21

1.12 (0.70, 1.77)

Active

1091

1.0 ref

550

1.0 ref

179

1.0 ref

124

1.0 ref

Age 30 to enrollment

        

Inactive

146

1.06 (0.89, 1.27)

79

1.15 (0.91, 1.46)

24

1.05 (0.69, 1.62)

11

0.72 (0.39, 1.33)

Active to inactive

347

1.04 (0.92, 1.18)

160

0.95 (0.79, 1.13)

64

1.27 (0.95, 1.69)

43

1.18 (0.83, 1.67)

Inactive to active

94

1.01 (0.82, 1.25)

55

1.19 (0.90, 1.57)

12

0.77 (0.43, 1.37)

11

1.01 (0.54, 1.87)

Active

1136

1.0 ref

562

1.0 ref

188

1.0 ref

136

1.0 ref

  1. aThe total number of breast cancer does not add up caused by missing information on PA at younger ages, age 14 to age 30 n = 77,272, age 14 to enrollment n = 77,623 and age 30 to enrollment n = 78,477.
  2. bInactive: very low or low PA level, Active: moderate, high or very high PA level.
  3. cThe multivariable model with RR and 95% CI used the attained age as the underlying time variable. Covariates adjusted for in the model were height, body mass index, smoking status, duration of smoking (pack years), age at smoking initiation, age at menarche, use of oral contraceptives, age at first birth, parity, use of hormone replacement therapy, self-reported disease and history of breast cancer in the participant’s mother.
  4. RR: relative risks; CI: confidence intervals.