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Table 4 Estrogen receptor (ER) and progesterone receptor (PR) status of breast tumor and PA level at age 14, age 30 and at enrollment among 1,767 breast cancer cases in the Norwegian Women and Cancer Study

From: Physical activity and the risk of postmenopausal breast cancer - the Norwegian Women and Cancer Study

  PA Level
ER/PR status N cases Very low Low Moderate High Very high P trend
ER+/PR+ a 872 56 188 373 208 47  
PA at enrollment   1.07 (0.81, 1.42) 0.94 (0.79, 1.12) 1.0 ref 0.95 (0.80, 1.12) 0.87 0(.65, 1.19) 0.49
PA at age 14   0.68 (0.40, 1.16) 0.74 (0.58, 0.95) 1.0 ref 1.02 (0.87, 1.20) 1.03 (0.85, 1.25) 0.02
PA at age 30   1.53 (1.00, 2.36) 1.10 (0.89, 1.40) 1.0 ref 0.95 (0.81, 1.12) 0.90 (0.71, 1.13) 0.04
ER+/PR- a 294 17 73 100 84 20  
PA at enrollment   1.32 (0.78, 2.22) 1.43 (1.06, 1.94) 1.0 ref 1.40 (1.04, 1.87) 1.32 (0.81, 2.13) 0.98
PA at age 14   0.83 (0.36, 1.88) 0.62 (0.40, 0.98) 1.0 ref 0.92 (0.70, 1.22) 1.28 (0.93, 1.76) 0.02
PA at age 30   1.21 (0.53, 2.75) 0.84 (0.57, 1.26) 1.0 ref 1.00 (0.76, 1.30) 1.03 (0.70, 1.51) 0.68
ER-/PR- a 206 8 47 91 52 8  
PA at enrollment   0.70 (0.34, 1.46) 1.03 (0.72, 1.47) 1.0 ref 0.94 (0.67, 1.32) 0.57 (0.28, 1.18) 0.51
PA at age 14   1.60 (0.73, 3.49) 1.06 (0.67, 1.70) 1.0 ref 1.10 (0.78, 1.54) 1.15 (0.76, 1.74) 0.94
PA at age 30   0.56 (0.14, 2.28) 0.78 (0.48, 1.27) 1.0 ref 0.90 (0.66, 1.24) 0.81 (0.50, 1.30) 0.97
  1. aMultivariable model with relative risks and 95% confidence intervals used the attained age as the underlying time variable. Covariates adjusted for in the model were height, body mass index, smoking status, smoking duration (pack years), age at menarche, use of oral contraceptives, age at first birth, parity, use of hormone replacement therapy, self-reported disease and history of breast cancer in the participant’s mother.