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Figure 1 | Journal of Negative Results in BioMedicine

Figure 1

From: Reduction in hSOD1 copy number significantly impacts ALS phenotype presentation in G37R (line 29) mice: implications for the assessment of putative therapeutic agents

Figure 1

Literature survey for details regarding the genomic SOD1 G37R locus. A review of publications (n = 25) listed on the Mouse Genome Informatics database over the preceding two decades in reference to G37R line 29 animals reveals: (1) discrete copy numbers have not been characterized, (2) SOD1 protein and/or aggregate levels are only assessed in half of the studies, and (3) given a genotype assessment, no values regarding relative transgene presence are reported.

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