The effects of dual inhibitors on T. cruzi epimastigotes after 72 h of treatment. (a) Baicalein considerably reduced protozoa proliferation in a dose-dependent manner. (b) Luteolin did not promote growth impairment. (c) Evodiamine caused a reduction of parasite proliferation, but values were very similar with different drug concentrations. The asterisks indicate drug addition to the culture medium. Data are the average of three independent experiments. DMSO, dimethyl sulfoxide.