Table 1 Overview of the reported baseline blood concentrations of CNP and NT-proCNP (mean ± SD)

Del Ry, 2012 [11]

0-3d

41

newborns

11.6 ± 2.1*^R

4-30d

24

newborns

16.4 ± 3.7*^R

1-12 m

22

infants

15.4 ± 2.7*^R

1-12

32

childrens

13.6 ± 2.3*^R

64 ± 1

32

healthy adults

7.4 ± 1.0*^R

64 ± 1

130

heart failure

7.86 ± 0.41*^R

67.1 ± 7.36

63 ± 2

19

diabetes

8.70 ± 1.62*^R

51.5 ± 5.75

52 ± 1

24

liver cirrhosis

4.97 ± 0.55*^R

78.4 ± 19.9

61 ± 2

73

healthy

2.35 ± 0.11*^R

45.5 ± 1.84

60 ± 15

40

RA

105 ± 189

30

healthy

50 ± 35

57 ± 10

52

erectile dysfunction

2.28 ± 0.87

matched

31

healthy

3.70 ± 0.76

64 ± 9

120

cardiovascular disease

1.43*^R,a

187.0^a

0.8-3.6

50

Malaria, severe

120 ± 72

0.8-2.0

39

Malaria, uncomplicated healthy

125.0 ± 49

25

0.8-6.4

155 ± 70

Yagci, 2008 [22]

34 ± 6

26

healthy

800 ± 270^E

34 ± 9

28

Behcet, active

490 ± 120^E

25

Behcet, inactive

650 ± 200^E

62 ± 2

51

ILVD

7.0 ± 0.9*^R

61 ± 2

60

healthy

2.5 ± 0.12*^R

13 ± 2

10

GHD baseline

339 ± 40

GHD under therapy

622 ± 157

14 ± 1

11

healthy

432 ± 64

35-60

44

Hyperlipidemia

4100 ± 5800*^E

matched

20

healthy controls

5700 ± 3300*^E

61 ± 2

21

healthy

2.7 ± 0.2*^R

33 - 91

22

heart failure

105 ± 5.4

25 - 55

16

healthy

80 ± 3.2

Gülberg, 2000 [15]

57 ± 2

20

liver cirrhosis, RI

2.7 ± 0.4*^R

52 ± 2

20

liver cirrhosis, no RI

3.0 ± 0.2*^R

45 ± 6

11

healthy

4.2 ± 0.4*^R

29 ± 2

12

healthy

997 ± 379^E

991 ± 489*^E

58.5 ± 28.3

60.3 ± 23.9

1933 ± 699°^E