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Table 3 Odds ratios (ORs) and 95% confidence intervals (CIs) for decreased eGFR (< 90 ml/min/1.73 m 2 ) by ND2-237 Leu/Met genotype and green tea consumption status

From: Unexpected combined effects of NADH dehydrogenase subunit-2 237 Leu/Met polymorphism and green tea consumption on renal function in male Japanese health check-up examinees: a cross-sectional study

Genotype and green tea consumption OR (95% CI) Adjusted OR (95% CI) Adjusted OR (95% CI)
ND2-237Leu
≤1 cup per day 1 (reference) 1 (reference) 1 (reference)
2–3 cups per day 1.957 (0.857–4.466) 1.777 (0.748–4.223) 2.240 (0.864–5.808)
4–5 cups per day 2.152 (0.849–5.453) 1.279 (0.457–3.578) 1.509 (0.502–4.533)
≥6 cups per day 4.598 (1.445–14.63)* 3.134 (0.938–10.47) 5.647 (1.528–20.88)**
  P for trend = 0.007 P for trend = 0.064 P for trend = 0.016
ND2-237Met
≤1 cup per day 1 (reference) 1 (reference) 1 (reference)
2–3 cups per day 2.250 (0.886–5.715) 2.251 (0.886–5.718) 2.943 (1.023–8.461)*
4–5 cups per day 1.540 (0.555–4.271) 1.499 (0.525–4.280) 1.136 (0.344–3.749)
≥6 cups per day 2.054 (0.687–6.143) 1.597 (0.490–5.204) 0.984 (0.260–3.721)
  P for trend = 0.256 P for trend = 0.500 P for trend = 0.903
  1. eGFR: estimated glomerular filtration rate. OR adjusted for age and body mass index. OR adjusted for age, body mass index, habitual smoking, alcohol consumption, coffee consumption and antihypertensive medication. *P < 0.05, **P < 0.01.