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Table 3 Odds ratios (ORs) and 95% confidence intervals (CIs) for decreased eGFR (< 90 ml/min/1.73 m 2 ) by ND2-237 Leu/Met genotype and green tea consumption status

From: Unexpected combined effects of NADH dehydrogenase subunit-2 237 Leu/Met polymorphism and green tea consumption on renal function in male Japanese health check-up examinees: a cross-sectional study

Genotype and green tea consumption

OR (95% CI)

Adjusted OR (95% CI)

Adjusted OR (95% CI)

ND2-237Leu

≤1 cup per day

1 (reference)

1 (reference)

1 (reference)

2–3 cups per day

1.957 (0.857–4.466)

1.777 (0.748–4.223)

2.240 (0.864–5.808)

4–5 cups per day

2.152 (0.849–5.453)

1.279 (0.457–3.578)

1.509 (0.502–4.533)

≥6 cups per day

4.598 (1.445–14.63)*

3.134 (0.938–10.47)

5.647 (1.528–20.88)**

 

P for trend = 0.007

P for trend = 0.064

P for trend = 0.016

ND2-237Met

≤1 cup per day

1 (reference)

1 (reference)

1 (reference)

2–3 cups per day

2.250 (0.886–5.715)

2.251 (0.886–5.718)

2.943 (1.023–8.461)*

4–5 cups per day

1.540 (0.555–4.271)

1.499 (0.525–4.280)

1.136 (0.344–3.749)

≥6 cups per day

2.054 (0.687–6.143)

1.597 (0.490–5.204)

0.984 (0.260–3.721)

 

P for trend = 0.256

P for trend = 0.500

P for trend = 0.903

  1. eGFR: estimated glomerular filtration rate. OR adjusted for age and body mass index. OR adjusted for age, body mass index, habitual smoking, alcohol consumption, coffee consumption and antihypertensive medication. *P < 0.05, **P < 0.01.