Clinical predictors of inflammatory bowel disease in a genetically well-defined Caucasian population

Table 5 Multivariable Logistic Regression Analysis for UC vs. CD

Genetic and Clinical Variables		Ulcerative Colitis vs. Crohn's Disease
		Estimate*	p -value	OR (95% CI)
*Age at time of diagnosis*	≥ 27	0.32	*0.04*	1.38 (1.02-1.87)
	< 27	0
*Gender*	Female	-0.38	*0.01*	0.68 (0.50-0.92)
	Male	0
*Smoker Status*	Current	-1.63	*< 0.0001*	0.20 (0.13-0.30)
	Former	-0.81	*< 0.0001*	0.45 (0.32-0.63)
	Never	0	*< 0.0001*
*Number of Operations*	Yes	-0.63	*0.002*	0.53 (0.36-0.79)
	No	0
*Family History IBD*	Yes	-0.88	*< 0.0001*	0.42 (0.30-0.57)
	No	0
*NOD2 - rs5743293*	C	-1.72	*0.0002*	0.18 (0.07-0.44)
	N	0
*NOD2 - rs2066844*	T	-0.60	*0.03*	0.55 (0.33-0.93)
	C	0
*NOD2 - rs2066845*	C	-1.30	*0.02*	0.271 (0.09-0.84)
	G	0

* A positive estimate indicates the variable being more predictive of ulcerative colitis while a negative estimate is more predictive of Crohn's disease.

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