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Table 2 Univariate Analysis of Allelic Association in SNPs

From: Clinical predictors of inflammatory bowel disease in a genetically well-defined Caucasian population

Single Nucleotide Polymorphism

Total # of Alleles (Total= 1644)

(N, %)

Control (Total= 582)

(N, %)

Crohn's Disease (Total= 654)

(N, %)

Ulcerative Colitis (Total= 408)

(N, %)

p-value

NOD2 - rs5743293

    

< 0.001 1

C

59 (4)

8 (1)

43 (7)

8 (2)

< 0.0001 2

N

1499 (96)

546 (99)

561 (93)

392 (98)

0.509 3

     

< 0.001 4

NOD2 - rs2066844

    

< 0.001 1

C

1377 (93)

466 (97)

545 (89)

366 (93)

< 0.001 2

T

109 (7)

14 (3)

67 (11)

28 (7)

0.004 3

     

0.042 4

NOD2 - rs2066845

    

< 0.001 1

G

1558 (98)

560 (99)

601 (96)

397 (99)

< 0.001 2

C

38 (2)

6 (1)

27 (4)

5 (1)

1.000 3

     

0.006 4

IL-23r - rs11465804

    

0.022 1

G

67 (4)

30 (5)

16 (3)

21 (5)

0.010 2

T

1545 (96)

534 (95)

630 (97)

381 (95)

0.948 3

     

0.019 4

  1. 1 Global (Fisher's Exact Test)
  2. 2 Control versus CD
  3. 3 Control versus UC
  4. 4 CD versus UC