Table 2 Characteristics of NGFR haplotype-tagging SNPs

rs2072445

rs2072446

(Ser205Leu)

rs734194

rs741072

rs741073

Nucleotide change

G→T

C→T

T→G

C→T

G→A

Location

Intron

Exon

3'UTR

3'UTR

3'UTR

HapMap CHB

   MAF

0.09

0.15

0.19

0.41

0.25

Controls

   MAF

0.07

0.11

0.29

0.30

0.24

   HWE P value

0.13

0.66

0.97

0.35

0.12

Cases

   MAF

0.08

0.11

0.25

0.34

0.25

   HWE P value

0.17

0.72

0.57

0.21

0.37